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Ruthenium-Catalyzed Asymmetric Hydrosilylation of Ketones and Imine

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journal contribution
posted on 09.07.1998, 00:00 by Yoshiaki Nishibayashi, Izuru Takei, Sakae Uemura, Masanobu Hidai
Ruthenium complexes with (oxazolinylferrocenyl)phosphines, RuCl2(PPh3)((oxazolinylferrocenyl)phosphine), have been prepared and characterized by spectroscopy. These ruthenium complexes are very effective catalysts for asymmetric hydrosilylation of not only ketones but also an imine to give the corresponding sec-alcohols (up to 97% ee) and a sec-amine (88% ee) after acid hydrolysis, respectively.