bi7b00493_si_001.pdf (477.57 kB)
Download file

RutA-Catalyzed Oxidative Cleavage of the Uracil Amide Involves Formation of a Flavin-N5-oxide

Download (477.57 kB)
journal contribution
posted on 29.06.2017, 00:00 by Sanjoy Adak, Tadhg P. Begley
RutA is a novel flavoenzyme on the uracil catabolic pathway that catalyzes uracil ring opening by a unique amide oxidation reaction. Here we provide evidence that this reaction also involves the formation of a flavin-N5-oxide.