cs6b00675_si_001.pdf (11.85 MB)

Room-Temperature meta-Functionalization: Pd(II)-Catalyzed Synthesis of 1,3,5-Trialkenyl Arene and meta-Hydroxylated Olefin

Download (11.85 MB)
journal contribution
posted on 27.04.2016, 00:00 by Milan Bera, Santosh K. Sahoo, Debabrata Maiti
Development of meta-C–H functionalization reactions at room temperature continues to be a tough challenge. Use of a phosphonate linkage allowed a Pd (II)-catalyzed meta-C–H functionalization at room temperature while incorporating a cyanophenol-based directing moiety. Successful implementation of sequential di-meta-olefination led to the synthesis of a trialkenyl arene, which has applications in organic electronics and optoelectronics. Under robust conditions, C–O bond formation has been discovered for the meta-hydroxylation and meta-acetoxylation.