American Chemical Society
ol503722r_si_001.pdf (4.02 MB)

Rhodium(III)-Catalyzed Oxidative Alkenylation of 1,3-Dithiane-Protected Arenecarbaldehydes via Regioselective C–H Bond Cleavage

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journal contribution
posted on 2015-02-06, 00:00 authored by Yuto Unoh, Koji Hirano, Tetsuya Satoh, Masahiro Miura
A Rh­(III)-catalyzed direct alkenylation of 2-aryl-1,3-dithiane derivatives with alkenes has been developed. The 1,3-dithiane group can serve as an effective directing group for the exclusively monoselective alkenylation under mild oxidative conditions. The directing group is readily removable after the coupling event.