posted on 2020-03-20, 15:39authored bySifeng Li, Qingjing Yang, Zhaoxiang Bian, Jun Wang
A highly efficient Rh(I)/(S)-xyl-Binap catalytic
system is developed for the asymmetric hydroselenation of various
nonpolar olefins with diselenides. Under these mild reaction conditions,
a wide range of heterobicyclic alkenes give selenol-incorporated adducts
in excellent enantioselectivities (up to 97%) along with high yields
(up to 96%) by overcoming self-promoted racemic hydroselenation. The
strategy is also applied for kinetic resolution of unsymmetric oxabenzonorbornadiene.