ol7b00438_si_001.pdf (5.45 MB)
Rhodium-Catalyzed Cycloadditions between 3‑Diazoindolin-2-imines and 1,3-Dienes
journal contribution
posted on 2017-03-29, 21:19 authored by Bo Lang, Huangtianzhi Zhu, Chen Wang, Ping Lu, Yanguang WangAzepino[2,3-b]indoles
were regioselectively prepared
through rhodium-catalyzed formal aza-[4 + 3] cycloaddition between
3-diazoindolin-2-imines and 1,3-dienes in moderate to good yields.
Using 2-[(trimethylsilyl)oxy]-1,3-butadiene as the diene component,
azepino[2,3-b]indol-4(1H)-ones were
constructed. Furthermore, the reactions of cyclic dienes, such as
1,3-cyclohexadiene and 1,3-cyclopentadiene, furnished the corresponding
[3 + 2] cycloaddition products.