posted on 2021-09-07, 21:31authored byYoshihiko Morimoto, Takuya Kochi, Fumitoshi Kakiuchi
Anti-Markovnikov hydroamination of
both aliphatic and aromatic
terminal alkynes with primary amines was achieved using an 8-quinolinolato
rhodium catalyst to form aldimines and enamines in high yields. This
catalytic system realized high functional group tolerance including
hydroxy, bromo, cyano, and thioester groups.