American Chemical Society
ol203199m_si_001.pdf (4.27 MB)

Rhenium-Catalyzed Regiodivergent Addition of Indoles to Terminal Alkynes

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journal contribution
posted on 2012-01-20, 00:00 authored by Dexin Xia, Yin Wang, Zhenting Du, Qi-Yu Zheng, Congyang Wang
An efficient rhenium-catalyzed site-switchable addition of indoles to terminal alkynes is described. A variety of bisindolylalkane derivatives are expeditiously synthesized in high yields with excellent regioselectivity. Preliminary mechanistic study sheds light on the observed regiodivergent addition.