ja204014s_si_001.pdf (2.47 MB)
Download fileReversible Redox of NADH and NAD+ at a Hybrid Lipid Bilayer Membrane Using Ubiquinone
journal contribution
posted on 2011-08-17, 00:00 authored by Wei Ma, Da-Wei Li, Todd C. Sutherland, Yang Li, Yi-Tao Long, Hong-Yuan ChenHere, we report the reversible interconversion between NADH and NAD+ at a low overpotential, which is in part mediated by ubiquinone embedded in a biomimetic membrane to mimic the initial stages of respiration. This system can be used as a platform to examine biologically relevant electroactive molecules embedded in a natural membrane environment and provide new insights into the mechanism of biological redox cycling.