American Chemical Society
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Reversible Redox of NADH and NAD+ at a Hybrid Lipid Bilayer Membrane Using Ubiquinone

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journal contribution
posted on 2011-08-17, 00:00 authored by Wei Ma, Da-Wei Li, Todd C. Sutherland, Yang Li, Yi-Tao Long, Hong-Yuan Chen
Here, we report the reversible interconversion between NADH and NAD+ at a low overpotential, which is in part mediated by ubiquinone embedded in a biomimetic membrane to mimic the initial stages of respiration. This system can be used as a platform to examine biologically relevant electroactive molecules embedded in a natural membrane environment and provide new insights into the mechanism of biological redox cycling.