posted on 2003-04-02, 00:00authored byJason M. Nolan, Daniel L. Comins
Heteronuclear multiple bond correlation (HMBC)
was used to determine the regiochemical outcome of palladium-catalyzed carbon−carbon bond formation between
2,4-dibromoquinolines and terminal acetylenes. The observed regioselectivity of these coupling reactions is opposite
to that reported in the literature for analogous reactions.