jo049677l_si_004.pdf (77.72 kB)
Download file

Regio- and Stereospecific Syntheses of syn- and anti-1,2-Imidazolylpropylamines from the Reaction of 1,1‘-Carbonyldiimidazole with syn- and anti-1,2-Amino Alcohols

Download (77.72 kB)
journal contribution
posted on 23.07.2004, 00:00 authored by Mark J. Mulvihill, Cara Cesario, Vanessa Smith, Patricia Beck, Anthony Nigro
The regio- and stereospecific conversion of syn- and anti-1,2-amino alcohols to their respective syn- and anti-1,2-imidazolylpropylamines via treatment with 1,1‘-carbonyldiimidazole is described. The rationale behind the regio- and stereospecific nature as well as the generality of the reaction is discussed.