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Redox-Neutral Indole Annulation Cascades

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journal contribution
posted on 23.02.2011, 00:00 by Michael C. Haibach, Indubhusan Deb, Chandra Kanta De, Daniel Seidel
Aminobenzaldehydes react with indoles in an unprecedented cascade reaction. This acid-catalyzed redox-neutral annulation proceeds via a condensation/1,5-hydride shift/ring-closure sequence. Polycyclic azepinoindoles and related compounds are obtained in a single step with good to excellent yields.