ol061803f_si_001.pdf (1.36 MB)
Download fileReal-Time Monitoring of Microwave-Promoted Suzuki Coupling Reactions Using in Situ Raman Spectroscopy
journal contribution
posted on 2006-09-28, 00:00 authored by Nicholas E. Leadbeater, Rebecca J. SmithThe progress of microwave-promoted Suzuki reactions has been monitored using an in situ Raman spectroscopy apparatus assembled from
commercially available components. It was possible to see if any reaction occurred and, if so, when it reached completion. In addition, the
monitoring technique has given us an insight into the reaction, confirming that, when run in aqueous media, the coupling is in competition
with the rapid deboronation of the boronic acid.