Ready Synthetic Access to Enantiopure Allylic α(F)-Branched Fluoroalkenes

Larnaud, Florent; Malassis, Julien; Pfund, Emmanuel; Linclau, Bruno; Lequeux, Thierry

doi:10.1021/ol400917j.s001

Ready Synthetic Access to Enantiopure Allylic α_(F)-Branched Fluoroalkenes

journal contribution

posted on 2016-02-19, 08:44 authored by Florent Larnaud, Julien Malassis, Emmanuel Pfund, Bruno Linclau, Thierry Lequeux

Convenient access to homochiral fluoroalkenes is described via a Julia–Kocienski olefination reaction. The required homochiral fluorosulfone is synthesized by a Mitsunobu reaction from readily available enantiopure secondary alcohols.

History

Usage metrics

Keywords

Allylic Access olefination Mitsunobu reaction access FluoroalkenesConvenient homochiral fluoroalkenes Enantiopure Julia enantiopure homochiral fluorosulfone Ready

Licence

CC BY-NC 4.0

Exports

RefWorks

BibTeX

Ref. manager

Endnote

DataCite

NLM

DC