ol7b03234_si_001.pdf (5.74 MB)
Rare Sulfur-Containing Compounds, Kujounins A1 and A2 and Allium Sulfoxide A1, from Allium fistulosum ‘Kujou’
journal contribution
posted on 2017-12-11, 19:59 authored by Masashi Fukaya, Seikou Nakamura, Ryota Nakagawa, Souichi Nakashima, Masayuki Yamashita, Hisashi MatsudaThree sulfur-containing compounds,
kujounins A1 (1) and A2 (2) and allium sulfoxide
A1 (3), were isolated from the acetone extract
of Allium fistulosum ‘Kujou’. Their
chemical structures were elucidated on the basis of physicochemical
evidence, including X-ray crystallographic data. Compounds 1 and 2 possess three rings and an acetal structure and
were obtained as complex compounds having disulfide and monosaccharide
moieties. On the other hand, compound 3 has a thiolane
skeleton derived from allicin. Naturally occurring compounds 1–3 have rare molecular skeletons. This
study is the first to determine the absolute configuration of thiolane-type
compounds.