posted on 2021-12-16, 22:30authored byTarannum Tasnim, Calvin Ryan, Miranda L. Christensen, Christopher J. Fennell, Spencer P. Pitre
Exploiting
charge-transfer complexes in visible light-promoted
single-electron redox reactions is a promising route for opening novel
synthetic pathways, and catalytic approaches to complex formation
are critical for facilitating this chemistry. This report describes
the use of a substituted hydroquinone catalyst to promote radical
perfluoroalkylation reactions. Mechanistic studies indicate that the
reaction is initiated through formation of a visible light-absorbing
halogen bonding complex between the hydroquinone catalyst and the
perfluoroalkyl halide radical precursor.