Progress toward the Total Synthesis of Kalihinane Diterpenoids

Studies toward the total synthesis of marine diterpenoids isolated from Acanthella sp., e.g., kalihinol A, are described. Efficient construction of the functionalized trans-decalin core (11) is achieved through intramolecular Diels−Alder cyclization followed by diastereoselective epoxidation and aziridination.