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Product Identification and Safety Evaluation of Aflatoxin B1 Decontaminated by Electrolyzed Oxidizing Water

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journal contribution
posted on 26.09.2012, 00:00 by Ke Xiong, Hai jie Liu, Li te Li
In this study with aflatoxin-contaminated peanuts, the effectiveness of electrolyzed oxidizing water (EOW) in the decontamination of aflatoxin B1 was investigated. The aflatoxin B1 content was markedly reduced upon treatment with EOW, particularly with neutral electrolyzed oxidizing water (NEW). The conversion product of EOW treatment was isolated and identified as 8-chloro-9-hydroxy aflatoxin B1 (compound 1), which is an amphiphilic molecule, in contrast to fat-soluble aflatoxin B1. A mutagenic response study revealed that the number of revertants per plate after treatment of bacterial strains TA-97, TA-98, TA-100, and TA-102 with NEW was within the standard value range. The HepG2 cell viability assay yielded an IC50 value of compound 1 approximately 150 mM. This study indicates that EOW had the ability to decontaminate aflatoxin B1, and the conversion product, compound 1, did not exhibit mutagenic activity or cytotoxic effects.

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