ol0275163_si_001.pdf (126.48 kB)
Probing the Diastereotopicity of Methylene Protons in Strychnine Using Residual Dipolar Couplings
journal contribution
posted on 2003-02-04, 00:00 authored by Christina M. Thiele, Stefan BergerResidual dipolar couplings were successfully used to distinguish between the two diastereotopic protons on C-20 of strychnine dissolved in
an organic liquid crystal (PBLG/CDCl3). The results presented here strongly suggest that this method will be of help in organic structure
determination, making the determination of relative stereochemistry in the absence of NOE data possible.