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Primary Structure Control of Oligomers Based on Natural and Synthetic Building Blocks

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journal contribution
posted on 18.03.2014, 00:00 by Delphine Chan-Seng, Jean-François Lutz
Solid-phase synthesis was exploited for the preparation of oligomers constructed from natural and synthetic building blocks by combining the formation of amide bonds and copper-assisted alkyne–azide cycloaddition reactions extending the variety of oligomers with well-defined primary structures accessible through this technique and providing control over the spacing between amino acids.