posted on 2012-06-15, 00:00authored byMasamichi Ogasawara, Mayuka Suzuki, Tamotsu Takahashi
Easily accessible 3-bromopenta-2,4-dienyl acetate was
applied to the palladium-catalyzed reaction with soft nucleophiles.
The reaction proceeded through the stepwise 2-fold nucleophilic substitution
via formal SN2′ and SN2 processes giving
the various doubly functionalized C2-symmetric
allenes in good yields.