ie0c02906_si_001.pdf (1.17 MB)
Preparation of 2,3-Epoxypropyl Neodecanoate: Process Optimization and Mechanism Discussion
journal contribution
posted on 2020-10-16, 14:36 authored by Zifei Yan, Jian Deng, Yuchao Chen, Guangsheng Luo2,3-Epoxypropyl
neodecanoate (EPDA) is an important synthon of
eco-friendly coatings, and its preparation methods and the relevant
reaction mechanisms remain to be further studied. In this work, the
two-step preparation method of EPDA is investigated. Under the optimized
process conditions in the acidolysis reaction, 99% conversion of neodecanoic
acid and 91–93% effective utilization rate of epichlorohydrin
could be realized. In the following ring-closure reaction, the two-step
alkali treatment was applied, and it can significantly reduce the
treatment time and improve the yield of EPDA by 3–5%. Besides,
the mechanism of the acidolysis reaction catalyzed by tetramethylammonium
chloride is proposed. The two chemical reaction pathways are put forward
to explain the formation of side product dichloropropanol. Two effective
ways to control the side reactions are suggested, including the control
of temperature in the range of 70–90 °C and reducing the
concentration of inorganic chlorine in the reaction system.