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Polymer-Supported Mukaiyama Reagent:  A Useful Coupling Reagent for the Synthesis of Esters and Amides

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journal contribution
posted on 25.11.2004, 00:00 by Stefano Crosignani, Jerome Gonzalez, Dominique Swinnen
Polymer-supported N-alkyl-2-chloro pyridinium triflate was synthesized in one step from Wang resin. This reagent proved to be a very effective coupling reagent for the synthesis of esters or amides from carboxylic acids and alcohols or amines (primary and secondary).

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