Platinum-Catalyzed Aromatization of Enediynes via
a C−H Bond Insertion of Tethered Alkanes

Taduri, Bhanu Pratap; Ran, Ying-Fen; Huang, Chun-Wei; Liu, Rai-Shung

doi:10.1021/ol052962m.s002

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Platinum-Catalyzed Aromatization of Enediynes via a C−H Bond Insertion of Tethered Alkanes

Version 2 2021-07-13, 18:07

Version 1 2016-05-05, 06:49

journal contribution

posted on 2021-07-13, 18:07 authored by Bhanu Pratap Taduri, Ying-Fen Ran, Chun-Wei Huang, Rai-Shung Liu

PtCl₂ (5 mol %) is an effective catalyst for aromatization of enediynes via a C−H bond insertion of tethered alkanes. The reaction mechanism of this cyclization is proposed to involve platinum−π-alkyne intermediates. This cyclization works not only for terminal alkynes but also for internal alkynes.