Pd(II)-Catalyzed Cycloisomerization/Dipolar Cycloaddition Cascade of N‑Arylnitrone Alkynes with Olefins

A cycloisomerization/dipolar cycloaddition tandem reaction of nitrone alkynes and electron-deficient olefins was described by employing a simple palladium catalyst. N-Arylnitrone alkynes, which were not well tolerated in previously reported methodologies, were successfully incorporated in the tandem reaction with generally good yields and moderate diastereoselectivities.