Pd/C-Catalyzed Deoxygenation of Phenol Derivatives Using Mg Metal and MeOH in the Presence of NH4OAc
journal contributionposted on 02.03.2006, 00:00 by Hironao Sajiki, Akinori Mori, Tomoteru Mizusaki, Takashi Ikawa, Tomohiro Maegawa, Kosaku Hirota
A Pd/C-catalyzed deoxygenation method of phenolic hydroxyl groups via aryl triflates or mesylates using Mg metal in MeOH at room temperature was developed. The addition of NH4OAc dramatically affects the reactivity and reaction rate. This method is particularly attractive to provide an environmentally benign and widely applicable removal method of phenolic alcohols under quite mild reaction conditions.