Palladium(III)-Catalyzed Fluorination of Arylboronic Acid Derivatives
journal contributionposted on 25.09.2013, 00:00 authored by Anthony R. Mazzotti, Michael G. Campbell, Pingping Tang, Jennifer M. Murphy, Tobias Ritter
A practical, palladium-catalyzed synthesis of aryl fluorides from arylboronic acid derivatives is presented. The reaction is operationally simple and amenable to multigram-scale synthesis. Evaluation of the reaction mechanism suggests a single-electron-transfer pathway, involving a Pd(III) intermediate that has been isolated and characterized.