Palladium-Catalyzed ortho-CH-Bond Oxygenation of Aromatic Ketones
journal contributionposted on 18.01.2013, 00:00 by Pui Ying Choy, Fuk Yee Kwong
A palladium-catalyzed C(sp2)–H bond oxygenation reaction is described. This protocol represents the first example of a C–H bond cleavage/C–O bond formation sequence, by employing a ketone moiety as the directing group. With this new catalytic method, a variety of ortho-acylphenols can be easily accessed from arylketones.