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Palladium-Catalyzed Synthesis of Benzosilolo[2,3-b]indoles via Cleavage of a C(sp3)–Si Bond and Consequent Intramolecular C(sp2)–Si Coupling

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journal contribution
posted on 22.06.2011, 00:00 by Yun Liang, Shaoguang Zhang, Zhenfeng Xi
An efficient process involving Pd-catalyzed selective cleavage of a C(sp3)–Si bond and consequent intramolecular C(sp2)–Si coupling has been developed, affording benzosilolo[2,3-b]indoles as a new type of silicon-bridged polyheteroarene in excellent yields. Aldehyde was found for the first time to be able to promote the efficiency of the catalytic process remarkably.