Palladium-Catalyzed Selective Acyloxylation Using Sodium Perborate as Oxidant
journal contributionposted on 04.03.2011, 00:00 by Lukasz T. Pilarski, Pär G. Janson, Kálmán J. Szabó
Sodium perborate (SPB), a principal component of washing powders, was employed as an inexpensive and eco-friendly oxidant in the palladium-catalyzed C−H acyloxylation of alkenes in excellent regio- and stereochemistry. The reactions used anhydrides as acyloxy sources. The method applies to both terminal and internal alkenes, and even benzylic C−H oxidation.