Palladium-Catalyzed Oxidative Domino Carbocyclization–Carbonylation–Alkynylation of Enallenes
journal contributionposted on 15.08.2014, 00:00 by Chandra M. R. Volla, Jan-E. Bäckvall
An oxidative carbocyclization–carbonylation–alkynylation reaction cascade has been developed using catalytic amounts of palladium(II) salts. The domino reaction proceeds efficiently, giving the corresponding ynones in good to excellent yields under operationally simple conditions. A wide range of aromatic and aliphatic terminal alkynes with various functional groups are tolerated under the reaction conditions.