Palladium Catalyzed Decarboxylative Rearrangement of N‑Alloc Indoles
journal contributionposted on 19.02.2016, 20:38 by Jun Chen, Matthew J. Cook
A highly efficient palladium catalyzed decarboxylative allylic rearrangement of alloc indoles has been developed. This can also be combined with a Suzuki–Miyaura cross-coupling reaction in a single pot transformation. Substituted alloc groups and benzylic variants have also been demonstrated alongside promising initial results on the enantioselective variant.