American Chemical Society
cs5019106_si_001.pdf (3.08 MB)

Palladium-Catalyzed Carbonylation of Indoles for Synthesis of Indol-3-yl Aryl Ketones

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journal contribution
posted on 2015-02-06, 00:00 authored by Mi-Na Zhao, Longfei Ran, Ming Chen, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan
A novel palladium-catalyzed carbonylation of indoles with CO and aromatic boronic acids for the synthesis of indol-3-yl aryl ketones was developed. The reaction tolerates a wide range of functional groups and gives a variety of valuable indol-3-yl aryl ketones in high yields under mild conditions.