American Chemical Society
ol0514597_si_001.pdf (174.35 kB)

Palladium-Catalyzed Annulation of Arynes by 2-Halobenzaldehydes:  Synthesis of Fluoren-9-ones

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journal contribution
posted on 2005-09-01, 00:00 authored by Xiaoxia Zhang, Richard C. Larock
Arynes, generated in situ from 2-(trimethylsilyl)aryl triflates and CsF, undergo annulation by o-haloarenecarboxaldehydes in the presence of a Pd catalyst, providing a useful new method for the synthesis of fluoren-9-ones in good yields.