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Oxygenated Sesquiterpenoids from a Nonpoisonous Sardinian Chemotype of Giant Fennel (Ferula communis)

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journal contribution
posted on 2001-02-08, 00:00 authored by Giovanni Appendino, Giancarlo Cravotto, Olov Sterner, Mauro Ballero
The roots of the nonpoisonous chemotype of giant fennel (Ferula communis) from Sardinia afforded a novel cadinanetriol (1), whose structure was established by spectroscopic data and confirmed by synthesis from the E,E1(10),5 germacradiene allohedycariol. A number of known compounds were also identified. Despite the lack of morphological differences, a broad chemical diversity exists within giant fennel, underlying the contrasting data on its poisonous properties.