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Oxime Derivatives as α-Electrophiles. From α-Tetralone Oximes to Tetracyclic Frameworks

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journal contribution
posted on 17.06.2011, 00:00 by Béatrice Quiclet-Sire, Nina Tölle, Syeda Nahid Zafar, Samir Z. Zard
When subjected to the conditions of a Semmler–Wolff/Schroeter aromatization, the oximes of 4-benzyl-substituted tetralones undergo an electrophilic aromatic substitution reaction to form tetracyclic frameworks.