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Oxazoline N-Oxide-Mediated [2+3] Cycloadditions. Application to a Synthesis of (−)-Tetrahydrolipstatin

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journal contribution
posted on 1999-07-31, 00:00 authored by O. Dirat, C. Kouklovsky, Yves Langlois
A [2+3] cycloaddition of camphor-derived oxazoline N-oxide to α,β-unsaturated ester afforded adduct 8. Tetrahydrolipstatin 1 was prepared from this compound in a nine-step sequence of reactions.

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