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Organocatalytic Asymmetric Strecker Reaction of Di- and Trifluoromethyl Ketoimines. Remarkable Fluorine Effect
journal contribution
posted on 2011-08-05, 00:00 authored by Yun-Lin Liu, Tao-Da Shi, Feng Zhou, Xiao-Li Zhao, Xin Wang, Jian ZhouA highly enantioselective Strecker reaction of difluoromethyl and trifluoromethyl ketoimines was developed. Remarkable fluorine effect on the reactivity and selectivity is observed and discussed.