Organocatalytic Asymmetric Strecker Reaction of Di- and Trifluoromethyl Ketoimines. Remarkable Fluorine Effect
journal contributionposted on 05.08.2011, 00:00 by Yun-Lin Liu, Tao-Da Shi, Feng Zhou, Xiao-Li Zhao, Xin Wang, Jian Zhou
A highly enantioselective Strecker reaction of difluoromethyl and trifluoromethyl ketoimines was developed. Remarkable fluorine effect on the reactivity and selectivity is observed and discussed.