posted on 2020-03-05, 14:39authored byMukesh
Eknath Shirbhate, Seongyeon Kwon, Ayoung Song, Seungha Kim, Dayeh Kim, Haofei Huang, Youngmee Kim, Hanna Lee, Sung-Jin Kim, Mu-Hyun Baik, Juyoung Yoon, Kwan Mook Kim
A novel multifunctional
aminophenylboronic acid connected to a
diphenylketone gives both circular dichroism and fluorescence signals
by in situ generation of a BODIPY-like chromophore in the presence
of aminoalcohols. DFT calculations were used to understand the role
of each functional group in the mechanism. This new sensor can distinguish
different aminoalcohols and quantitatively indicate the concentration
of the substrate, allowing for the convenient determination of the
ee of racemic mixtures with a single probe.