posted on 2007-02-15, 00:00authored byJonathan Rosen, Dietrich Steinhuebel, Michael Palucki, Ian Davies
A direct and efficient method was developed for the preparation of a variety of substituted acetophenone derivatives from readily available
arene precursors and acid chlorides. This method has significant generality and affords access to substitution patterns on aryl rings not
directly achievable by Friedel−Crafts chemistry.