One-Pot Synthesis of Symmetric and Unsymmetric 1,1-Bis-indolylmethanes via Tandem Iron-Catalyzed C−H Bond Oxidation and C−O Bond Cleavage

Guo, Xingwei; Pan, Shiguang; Liu, Jinhua; Li, Zhiping

doi:10.1021/jo902093p.s001

One-Pot Synthesis of Symmetric and Unsymmetric 1,1-Bis-indolylmethanes via Tandem Iron-Catalyzed C−H Bond Oxidation and C−O Bond Cleavage

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posted on 2009-11-20, 00:00 authored by Xingwei Guo, Shiguang Pan, Jinhua Liu, Zhiping Li

The reactions of indoles with ethers give a variety of symmetric and unsymmetric 1,1-bis-indolylmethane derivatives via iron-catalyzed C−H bond oxidation and C−O bond cleavage.

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Symmetric ether indole variety Oxidation Tandem derivative Synthesi oxidation CleavageThe unsymmetric Unsymmetric Bond cleavage bond

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One-Pot Synthesis of Symmetric and Unsymmetric 1,1-Bis-indolylmethanes via Tandem Iron-Catalyzed C−H Bond Oxidation and C−O Bond Cleavage

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