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One-Pot Synthesis of Arylketones from Aromatic Acids via Palladium-Catalyzed Suzuki Coupling

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journal contribution
posted on 05.03.2016, 00:00 by Hongxiang Wu, Baiping Xu, Yue Li, Fengying Hong, Dezhao Zhu, Junsheng Jian, Xiaoer Pu, Zhuo Zeng
A palladium-catalyzed one-pot procedure for the synthesis of aryl ketones has been developed. Triazine esters when coupled with aryl boronic acids provided aryl ketones in moderate to excellent yields (up to 95%) in the presence of 1 mol % Pd­(PPh3)2Cl2 for 30 min.