ol800754w_si_001.pdf (1.39 MB)

One-Pot Syntheses of 2,3-Dihydrothiopyran-4-one Derivatives by Pd/Cu-Catalyzed Reactions of α,β-Unsaturated Thioesters with Propargyl Alcohols

Download (1.39 MB)
journal contribution
posted on 19.06.2008, 00:00 by Yasunori Minami, Hitoshi Kuniyasu, Nobuaki Kambe
2,3-Dihydrothiopyran-4-one derivatives were readily prepared by Pd/Cu-catalyzed reactions between α,β-unsaturated thioesters and propargyl alcohols in the presence of bases. Of note, both carbon−sulfur bonds were cleaved as a result of the single procedure.

History