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Download fileOne-Pot Synthesis of 3‑Methyl-2-arylimidazo[1,2‑a]pyridines Using Calcium Carbide as an Alkyne Source
journal contribution
posted on 2021-12-22, 08:03 authored by Wei Chen, Zheng LiAn efficient method for the construction
of 3-methyl-2-arylimidazo[1,2-a]pyridines from the
reactions of calcium carbide, 2-aminopyridines,
and aromatic aldehydes is described. The notable advantages for this
strategy include the use of an inexpensive and concise solid alkyne
source, cheap and readily available raw materials, wide-scope substrates,
and a simple work-up procedure.