ol015814e_si_001.pdf (92.06 kB)
Download file

One-Pot, Catalytic, Asymmetric Synthesis of Polypropionates

Download (92.06 kB)
journal contribution
posted on 10.04.2001, 00:00 by Michael A. Calter, Xin Guo, Wensheng Liao
The opening of methylketene dimer, followed by aldol reactions of the resulting enolate, provides a convenient access to syn,syn-dipropionate aldol adducts of a variety of aldehydes. These aldol adducts are useful precursors in the synthesis of complex polypropionates.