Oligomannan Synthesis Using Ionic Liquid Supported Glycosylation§
journal contributionposted on 03.01.2008, 00:00 by Ashish K. Pathak, Charu K. Yerneni, Zac Young, Vibha Pathak
The synthesis of complex oligosaccharides has been a challenge for researchers. Herein, we describe a strategy for the synthesis of an activated oligomannan 1 that employs ionic liquid (IL) support glycosylation methodology on an IL-tagged mannosyl fluoride donor. This method is capable of rapidly producing linear α(1→6) oligomannan thioglycosides in a convenient and cost-effective manner without the need of column purification after each glycosylation step.