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Novel One-Step Synthesis of Thiazolo[3,2-b]1,2,4-triazoles

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journal contribution
posted on 02.02.2000, 00:00 by Alan R. Katritzky, Alfredo Pastor, Michael Voronkov, Peter J. Steel
Reactions of chalcones 3af with bis(1H-1,2,4-triazolyl) sulfoxide 4 formed the thiazolo[3,2-b]1,2,4-triazoles 5af, which resemble closely some previously prepared COX-2 inhibitors. The structure of 5a was confirmed by X-ray analysis.

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