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Notoamides F−K, Prenylated Indole Alkaloids Isolated from a Marine-Derived Aspergillus sp.

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journal contribution
posted on 26.12.2008, 00:00 by Sachiko Tsukamoto, Hikaru Kato, Masayuki Samizo, Yuka Nojiri, Hiroyuki Onuki, Hiroshi Hirota, Tomihisa Ohta
Six new prenylated indole alkaloids, named notoamides F−K (813), were isolated from a marine-derived Aspergillus sp. Their structures, including absolute configurations, were elucidated by spectroscopic methods. Notoamide I (11) showed weak cytotoxicity against HeLa cells with an IC50 value of 21 μg/mL.

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