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New Ligands Bearing Chiral Bioactive Fragments

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journal contribution
posted on 24.05.2001, 00:00 authored by Abderrahim Khatyr, Raymond Ziessel
Reliable and practical synthetic routes for the construction of hybrid molecules bearing both a chelating center and a useful biofunction are presented. They comprise the sequential cross-coupling reaction between ethynylated synthons with iodo-substituted l-tyrosine derivatives and provide access to various rationally designed chiral ligands.